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As most variants identified by GWAS lie outside of protein-coding regions , it is likely that many of these SNPs may reside in as yet-unidentified regulatory elements where transcription factors and chromatin modifiers interact. Addressing these questions will provide a better understanding of the mechanisms underlying cardiovascular disease pathogenesis that will allow the development of better diagnostic tools and therapeutics to address this global health burden.

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Heart disease and stroke statistics — update. A report from the American Heart Association.

Circulation 4 :e38— An operational definition of epigenetics.

Detecting coordinated regulation of multi-protein complexes using logic analysis of gene expression

Genes Dev 23 7 —3. Series in Molecular Biology. J Mol Recognit. Google Scholar. Epigenetic regulation of pluripotency and differentiation.

Circ Res 2 — Wu H, Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev 25 23 — Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 76 1 — Jenuwein T, Allis CD. Translating the histone code. Science — Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease.

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Eur Heart J 30 3 — Greco CM, Condorelli G. Epigenetic modifications and noncoding RNAs in cardiac hypertrophy and failure. Nat Rev Cardiol 12 8 — Readers, writers, and erasers: chromatin as the whiteboard of heart disease. Circ Res 7 — Epigenetic regulation of smooth muscle cell plasticity.

Biochim Biophys Acta 4 — Epigenetic control of smooth muscle cell identity and lineage memory. Arterioscler Thromb Vasc Biol 35 12 — Epigenetics in the vascular endothelium. Looking from a different perspective in the epigenomics era. Arterioscler Thromb Vasc Biol 35 11 — Regulation of fetal gene expression in heart failure. Biochim Biophys Acta 12 — Epstein JA. Cardiac development and implications for heart disease. N Engl J Med 17 — J Biol Chem 13 — Biochim Biophys Acta 9 — UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program.

Dev Cell 22 1 — The neuron-restrictive silencer element—neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. Mol Cell Biol 21 6 — J Mol Cell Cardiol 41 6 — The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet 10 1 — Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell 19 3 —9.

Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. Hypertension 53 3 — Smith CL. A shifting paradigm: histone deacetylases and transcriptional activation. Bioessays 30 1 — Chromatin modifications remodel cardiac gene expression. Cardiovasc Res 1 :7— Eom GH, Kook H. Posttranslational modifications of histone deacetylases: implications for cardiovascular diseases. Pharmacol Ther 2 — McKinsey T.

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  • Gene regulation in bacteria.

Therapeutic potential for HDAC inhibitors in the heart. Annu Rev Pharmacol Toxicol 52 1 — Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation 1 —9. Regulation of vascular smooth muscle cell differentiation. J Vasc Surg 45 6 Suppl :A25— Vascular smooth muscle cells in atherosclerosis. Circ Res 4 — Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84 3 — Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation.

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  5. Qiu P, Li L. Circ Res 90 8 — Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol 25 1 — Acetylation of myocardin is required for the activation of cardiac and smooth muscle genes. J Biol Chem 46 — Platelet-derived growth factor-BB represses smooth muscle cell marker genes via changes in binding of MKL factors and histone deacetylases to their promoters.

    Circ Res 6 — J Clin Invest 1 — Cell Res 21 10 — Biochem Biophys Res Commun 2 —8. Circ Res 12 Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis. Cardiovasc Res 90 3 — Cell Adh Migr 9 5 —9. Gene 1 — Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev 86 1 — EMBO J 31 12 — Parmalee NL, Kitajewski J. Wnt signaling in angiogenesis. Curr Drug Targets 9 7 — Systemic effects of Wnt signaling. J Cell Physiol 7 — Regulation of Myf5 early enhancer by histone acetyltransferase p during stem cell differentiation. Mol Biol Mol Cell Biol 30 2 — J Cell Biol 2 — Blood 3 — AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p Arterioscler Thromb Vasc Biol 31 12 — Ewart M-A, Kennedy S.

    Overview: Gene regulation in bacteria

    AMPK and vasculoprotection. Activation of p histone acetyltransferase activity is an early endothelial response to laminar shear stress and is essential for stimulation of endothelial nitric-oxide synthase mRNA transcription. J Biol Chem 24 —8. Shear stress and the endothelium.

    Gene Regulation

    Kidney Int 54 Suppl 67 :S—8. Endothelial cell sensing of flow direction.

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    Arterioscler Thromb Vasc Biol 33 9 —6. Hahn C, Schwartz MA. Mechanotransduction in vascular physiology and atherogenesis. Nat Rev Mol Cell Biol 10 1 — J Biol Chem 1 —8. Reactive oxygen species in cardiovascular disease.